Peptides Anti-Aging & LongevityHormone SupportMuscle Building Preclinical (animal) data

Testagen

4.1 hours

Half-life

0.5–2 mg

Typical dose

10–20 days per course, repeated 2–3× yearly (reported)

Cycle length

Peptide bioregulator researched for testicular function and hormonal support.

Key takeaways

Synthetic testis-targeted tetrapeptide (Lys-Glu-Asp-Gly) from the Khavinson bioregulator program.
No human evidence it affects testosterone, fertility, or the HPG axis.
Plotter values are estimates modeled on similar short peptides, not measured human PK.
Reported 10–20 day courses are anecdotal; no established human dosing exists.

🚧 Expanded guide coming soon. This compound has PK data and a source — a full overview, mechanism, and dosing guide is pending editorial review.

Reported dosing protocols

Protocols reported in research literature and clinic/community use — informational context, not a dosing recommendation.

Use case	Dose	Route	Frequency	Duration
Testicular / hormonal support (community)	1–2 mg	SubQ; oral capsules also sold	Once daily	10–20 days, repeated 2–3× yearly

Pharmacokinetic summary

Model tier: Simple (t½ + F, Tmax estimated)
Half-life: 4.1 hours
Bioavailability: 40%
Typical dose: 0.5–2 mg

Frequently asked questions

Does Testagen raise testosterone?

There's no evidence it does. No human study has measured testosterone after Testagen, and the preclinical work doesn't demonstrate HPG-axis effects. Claims online are marketing, not data.

Can Testagen help with fertility?

No clinical evidence supports that. Male-factor infertility has established workups and treatments; Testagen has never been tested in a randomized fertility trial.

Is Testagen suppressive like steroids?

No data shows HPG suppression either, since it isn't a hormone and has no demonstrated endocrine activity in humans. The honest answer is that its endocrine effects, good or bad, are unstudied.

References

Estimated (bioregulator) — Testicular/HPG-axis peptide bioregulator.
Biochemistry (Mosc) 2011 — short peptides penetrate the cell nucleus — Confirms Testagen's KEDG sequence and shows nuclear penetration in HeLa cells; mechanism-level work, not efficacy.
Khavinson & Popovich, Molecules 2021 — Peptide Regulation of Gene Expression: A Systematic Review — Maps Testagen (KEDG) to testicular gene regulation; summarizes the single-group literature.

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