Testosterone Suspension
Test Base (injectable) · Aquadose
Ester-free injectable testosterone (water base). Very sharp peaks; dosed daily.
Key takeaways
- Ester-free testosterone in water; fastest onset of any injectable, peaking around 6 hours.
- Apparent ~33-hour half-life; daily injection is standard, and the curve leans on animal data.
- Sharp daily peaks drive bigger estradiol and hematocrit swings than esters.
- Water base plus daily injections: sterile technique matters most here.
Reported dosing protocols
Protocols reported in research literature and clinic/community use — informational context, not a dosing recommendation.
| Use case | Dose | Route | Frequency | Duration |
|---|---|---|---|---|
| Pre-event / rapid onset (community) | 25–100 mg | IM | Daily, sometimes split 2× | 2–6 weeks reported |
Pharmacokinetic summary
- Model tier
- Advanced (t½ + Cmax + Tmax + F)
- Half-life
- 33 hours
- Cmax
- 900 ng/dL
- Tmax
- 0.3 days
- Bioavailability
- 100%
- Typical dose
- 25–100 mg
Harm reduction
- Aromatizes
- Yes
- DHT derivative
- No
- Injection frequency
- Daily
Frequently asked questions
Why does suspension hurt more than esters?
Two reasons: the water base carries no oil to buffer the depot, and testosterone base crystals can sit in the muscle before dissolving. Reports of post-injection pain are consistently worse than with oil-based esters, though severity varies by product and site.
Does suspension clear faster for drug testing?
Not meaningfully. The parent testosterone clears in days, but anti-doping tests track the T/E ratio and carbon-isotope signature, which stay abnormal well past the last injection. The idea that no ester means no detection is a myth.
Is the suspension half-life really 33 hours?
That figure is an apparent half-life: it describes how fast the depot absorbs and declines, not true elimination of testosterone, which runs in minutes to hours. It's also calibrated partly from equine data, so the human curve is approximate.
References
- RMTC equine PK study — Cmax calibrated to ng/dL serum peak (ester-free water base → sharp spike).
- RMTC interlaboratory testosterone PK study (equine) — Horse data behind the absorption profile; no equivalent modern human study exists.
- Pharmacology of testosterone replacement therapy preparations (TAU 2016) — General review of testosterone preparation PK.
Related compounds
Testosterone Enanthate
Long-acting testosterone ester; the most common TRT and cycle base. Reaches steady state in ~5 weeks.
Testosterone Cypionate
Standard US TRT ester with a slightly longer release tail than enanthate. Steady state ~4–5 weeks.
Testosterone Propionate
Short-acting ester with sharp peaks; requires frequent injection. Useful for frontloading.
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