Anabolic Steroids/Hormones Preclinical (animal) data

Trenbolone Hexahydrobenzylcarbonate

Tren Hex · Parabolan

8 days

Half-life

100–300 mg

Typical dose

2×/week

Frequency

8–12 weeks

Cycle length

Long-acting trenbolone (original Parabolan). Simple model — peak calibrated.

Key takeaways

Longest trenbolone ester; the original Parabolan, the only trenbolone ever marketed for human use.
~8-day half-life; twice-weekly injection, slow build to steady state and a slow exit.
No aromatization or 5-alpha-reduction; cardiovascular, renal, and psychological effects dominate.
Human evidence is thin — plotter values are a calibrated model, not measured data.

🚧 Expanded guide coming soon. This compound has PK data and a source — a full overview, mechanism, and dosing guide is pending editorial review.

Reported dosing protocols

Protocols reported in research literature and clinic/community use — informational context, not a dosing recommendation.

Use case	Dose	Route	Frequency	Duration
Cachexia / osteoporosis (historical label)	76 mg ampoule (~50 mg base)	IM	Every 10 days	Weeks–months
Performance (community)	150–300 mg weekly	IM	2× weekly	8–12 weeks

Pharmacokinetic summary

Model tier: Simple (t½ + F, Tmax estimated)
Half-life: 8 days
Cmax: 113.5 ng/dL
Bioavailability: 66%
Typical dose: 100–300 mg

Harm reduction

Aromatizes: No
DHT derivative: No
Hepatotoxicity: mild
Injection frequency: 2×/week

⚠ Trenbolone + PDE5 inhibitors (e.g. tadalafil) raises cardiovascular risk.

Frequently asked questions

How is Tren Hex different from trenbolone enanthate?

Barely. Both are long esters injected twice weekly, and the active hormone is identical. Hex's distinction is historical: it was the Parabolan ester, the only trenbolone formulation ever sold for human use. The practical difference in clearance time is minor.

Does trenbolone convert to estrogen?

No. It doesn't aromatize and isn't 5-alpha-reduced. But it does bind the progesterone receptor, so progestogenic effects like gynecomastia can still occur even with no estrogen conversion.

Why do some users avoid the long trenbolone esters?

Clearance time. With a ~8-day half-life, side effects like insomnia, blood pressure spikes, or mood changes persist for weeks after the last injection. Acetate clears in days, which is why it's the more common choice despite the injection frequency.

References

Trenbolone ester PK — Cmax calibrated to ng/dL serum peak.
Trenbolone ester PK / metabolism study — Source of the ester PK values behind the calibrated curve.

Trenbolone: Acetate vs Enanthate vs Hexahydrobenzylcarbonate

9 min read

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